What is certain in presentation of a lecture or conference and …  is that it can be presented in different ways. Examining the effect of the presentation on the audience and whether it covers the intended objectives or not. The science of presentation according to brain knowledge helps us to provide enough knowledge about the effects of presentation before presenting. For example, you can find out how much u can influence to your audience before a speech and changed the text and presentation method to achieve maximum impact on the desired goals. This method by considering the changes in senses and brain reactions can predict the human response to the presentation.